Thinnex Insights

The Science of Weight Loss

Evidence-based guides on GLP-1, GLP-3, peptide therapy, and metabolic medicine — written by our clinical team.

🔬 Deep Dive
July 2026 9 min read

What Is GLP-3? The Triple Agonist Outperforming Semaglutide and Tirzepatide

GLP-3 (retatrutide) activates three receptor pathways simultaneously — GLP-1, GIP, and glucagon. Phase 2 trial data published in the NEJM showed 24.2% average body weight loss. Here's what that means, and why almost no one is talking about it yet.

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⚖️ Head-to-Head
July 2026 10 min read

Semaglutide vs. Tirzepatide: Which GLP-1 Is Right for You in 2026?

Both are GLP-1 receptor agonists. Both work. But they operate through different mechanisms and produce different clinical outcomes. If you're deciding between them, this breakdown gives you everything you need — science, side effects, cost, and who each one is best for.

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